The use of magnesium sulfate in medicine

2021-02-04 10:48

When patients with cardiac insufficiency use digitalis drugs, appropriate supplementation of magnesium salts can be used to prevent low magnesium from aggravating the toxicity of digitalis. Clinically, magnesium salt is often effective in the treatment of tachycardia.


Magnesium sulfate can stimulate the duodenal mucosa, reflexively cause the common bile duct sphincter to relax and the gallbladder to contract, thereby promoting the emptying of the gallbladder and benefiting the gallbladder. It can be used to treat cholecystitis and cholelithiasis, 2 to 5 grams each time, 3 times a day, orally before meals or between meals. 50% magnesium sulfate is diluted to 33% (high concentration), 5ml Tid.


Magnesium sulfate can be used for gastrointestinal imaging.


Anti-inflammation and swelling The 50% solution of this product is applied to the affected area for external application and has the effect of anti-inflammatory and swelling. External application of magnesium sulfate powder can reduce swelling, and is used to treat swelling after limb injuries and help improve rough skin.


Magnesium sulfate is easily soluble in water, but not absorbed by oral administration. Magnesium ions and sulfate ions in the aqueous solution are not easily absorbed by the intestinal wall, which increases the osmotic pressure in the intestine, and the water in body fluid moves to the intestinal cavity, which increases the volume of the intestinal cavity. The intestinal wall expands, thereby stimulating the afferent nerve endings in the intestinal wall, reflexively causing increase in bowel motility and catharsis. Its effect is on all intestinal segments, so the effect is fast and strong. Used as a catharsis agent and duodenal drainage agent.


Magnesium sulfate intravenous injection and intramuscular injection are mainly used for anti-convulsions. It can cause vasodilatation and lower blood pressure. Due to the central inhibitory effect of magnesium sulfate, skeletal muscle relaxation and blood pressure reduction, it is mainly used clinically to relieve eclampsia and tetanus. Other convulsions are also used for the treatment of hypertensive crisis. It is also used to detoxify barium salt.